Road Runner and Wile E. Coyote

Road Runner and Wile E. Coyote may refer to:
 * Wile E. Coyote and Road Runner: a coyote and greater road runner respectively who are two of main cast of the Looney Tunes theatrical shorts.
 * Road Runner and Wile E. Coyote: 2011 segments of The Looney Tunes Show